Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00199 |
Fc gamma RIIB/CD32b Protein, Human, Recombinant (His & Avi)
CDw32,Fc γ RIIB,Fc gamma... |
Human | HEK293 Cells |
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma RI (also known as CD64), Fc gamma RII (CD32), and Fc gamma RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. Fc gamma RIIB/CD32b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.5 kDa and... | |||
TMPY-01985 |
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated
FCGR2,FCGR21,CD32A,FCG2,CDw32,CD3... |
Human | HEK293 Cells |
CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2. | |||
TMPK-00200 |
Fc gamma RIIB/CD32b Protein, Human, Recombinant (His & Avi), Biotinylated
Fc γ RII,FCG2,FCGR2,Fc <... |
Human | HEK293 Cells |
Fc gamma RIIB/CD32b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.5 kDa and the accession number is P31994-1. | |||
TMPJ-00192 |
CD32B Protein, Human, Recombinant (His)
FCG2,IgG Fc Receptor II-b,CDw32,Low Affini... |
Human | HEK293 Cells |
FcγRIIB is a low affinity receptor that recognizes the Fc portion of IgG. The human CD32 group consists of FcγRIIA, FcγRIIB, and FcγRIIC proteins that share 94-99% sequence identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. FcγRII protein is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. FcγRIIB has an intrinsic cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM)... | |||
TMPJ-00803 |
CD32B Protein, Mouse, Recombinant (His)
Fcgr2,Fcgr2b,Fc-γ-RIIB,<... |
Mouse | HEK293 Cells |
Low affinity immunoglobulin gamma Fc region receptor II (CD32B) is a single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains. The inhibitory CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target formonoclonal antibody therap... | |||
TMPY-00765 |
CD32B/Fcgr2b Protein, Human, Recombinant (His)
IGFR2,FCGR21,Fc γ RIIB,Fc |
Human | HEK293 Cells |
CD32B/Fcgr2b Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.8 kDa and the accession number is P31994-2. | |||
TMPK-01115 |
Fc gamma RIII/CD16 Protein, Cynomolgus, Recombinant (His)
FcgRIII,FCR-10,FcRIII,IMD20,F... |
Cynomolgus | HEK293 Cells |
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set of IgG1 residues is involved in binding to all Fc gamma R; Fc gamma RII and Fc gamma RIII also utilize residues outside this common set. |